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Hec1 Polyclonal Antibody

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说明书下载
货号: PD5378
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Hec1
应用: WB,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 73kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Hec1 Polyclonal Antibody detects endogenous levels of Hec1 protein.
基因名称 : NDC80
蛋白名称 : Kinetochore protein NDC80 homolog
别名 : NDC80;HEC;HEC1;KNTC2;Kinetochore protein NDC80 homolog;Highly expressed in cancer protein;Kinetochore protein Hec1;HsHec1;Kinetochore-associated protein 2;Retinoblastoma-associated protein HEC

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011],

细胞定位 : Nucleus . Chromosome, centromere, kinetochore . Localizes to kinetochores from late prophase to anaphase (PubMed:14699129). Localizes specifically to the outer plate of the kinetochore (PubMed:14699129). .

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