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GCN5 Polyclonal Antibody

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说明书下载
货号: PD5597
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: GCN5
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 100kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : GCN5 Polyclonal Antibody detects endogenous levels of GCN5 protein.
基因名称 : KAT2A
蛋白名称 : Histone acetyltransferase KAT2A
别名 : KAT2A;GCN5;GCN5L2;HGCN5;Histone acetyltransferase KAT2A;General control of amino acid synthesis protein 5-like 2;Histone acetyltransferase GCN5;HsGCN5;Lysine acetyltransferase 2A;STAF97

数据库链接:

Organism

基因 ID

SwissProt

背景:

KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]).[supplied by OMIM, Sep 2009],

细胞定位 : Nucleus . Chromosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Mainly localizes to the nucleus (PubMed:27796307). Also localizes to centrosomes in late G1 and around the G1/S transition, coinciding with the onset of centriole formation (PubMed:27796307). .

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