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Factor VIII Polyclonal Antibody

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说明书下载
货号: PD5778
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Factor VIII
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 300kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Factor VIII Polyclonal Antibody detects endogenous levels of Factor VIII protein.
基因名称 : F8
蛋白名称 : Coagulation factor VIII
别名 : F8;F8C;Coagulation factor VIII;Antihemophilic factor;AHF;Procoagulant component

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008],

细胞定位 : Secreted, extracellular space.

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