产品服务
信号通路
说明书下载
货号: PD5923
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: EDG-8
应用: IHC,IF,ELISA
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(CalcμLated) : 42kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : EDG-8 Polyclonal Antibody detects endogenous levels of EDG-8 protein.
基因名称 : S1PR5
蛋白名称 : Sphingosine 1-phosphate receptor 5
别名 : S1PR5;EDG8;Sphingosine 1-phosphate receptor 5;S1P receptor 5;S1P5;Endothelial differentiation G-protein-coupled receptor 8;Sphingosine 1-phosphate receptor Edg-8;S1P receptor Edg-8
背景:
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008],


微信客服