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Duffy Polyclonal Antibody

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说明书下载
货号: PD5967
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Duffy
应用: IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 36kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications;
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Duffy Polyclonal Antibody detects endogenous levels of Duffy protein.
基因名称 : DARC
蛋白名称 : Duffy antigen/chemokine receptor
别名 : DARC;FY;GPD;Duffy antigen/chemokine receptor;Fy glycoprotein;GpFy;Glycoprotein D;Plasmodium vivax receptor;CD antigen CD234

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene is a glycosylated membrane protein and a non-specific receptor for several chemokines. The encoded protein is the receptor for the human malarial parasites Plasmodium vivax and Plasmodium knowlesi. Polymorphisms in this gene are the basis of the Duffy blood group system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位 : Early endosome. Recycling endosome. Membrane; Multi-pass membrane protein. Predominantly localizes to endocytic vesicles, and upon stimulation by the ligand is internalized via caveolae. Once internalized, the ligand dissociates from the receptor, and is targeted to degradation while the receptor is recycled back to the cell membrane.

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