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DNA pol δ Polyclonal Antibody

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说明书下载
货号: PD6008
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: DNA pol δ cat
应用: WB,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 110 124kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : DNA pol δ cat Polyclonal Antibody detects endogenous levels of DNA pol δ cat protein.
基因名称 : POLD1
蛋白名称 : DNA polymerase delta catalytic subunit
别名 : POLD1;POLD;DNA polymerase delta catalytic subunit;DNA polymerase subunit delta p125

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes the 125-kDa catalytic subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Mar 2012],

细胞定位 : Nucleus . Colocalizes with PCNA and POLD3 at S phase replication sites (PubMed:11595739). After UV irradiation, recruited to DNA damage sites within 2 hours, independently on the cell cycle phase, nor on PCNA ubiquitination. This recruitment requires POLD3, PCNA and RFC1-replication factor C complex (PubMed:20227374, PubMed:22801543). .

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