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CYP2C8 Polyclonal Antibody

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说明书下载
货号: PD6154
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: CYP2C8
应用: IHC,IF,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(CalcμLated) : 56kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC: 1:100-1:300;IF 1:50-200;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : CYP2C8 Polyclonal Antibody detects endogenous levels of CYP2C8 protein.
基因名称 : CYP2C8
蛋白名称 : Cytochrome P450 2C8
别名 : CYP2C8;Cytochrome P450 2C8;CYPIIC8;Cytochrome P450 IIC2;Cytochrome P450 MP-12;Cytochrome P450 MP-20;Cytochrome P450 form 1;S-mephenytoin 4-hydroxylase

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],

细胞定位 : Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

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