产品服务
信号通路
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : CRSP77 Polyclonal Antibody detects endogenous levels of CRSP77 protein.
基因名称 : MED17
蛋白名称 : Mediator of RNA polymerase II transcription subunit 17
别名 : MED17;ARC77;CRSP6;DRIP77;DRIP80;TRAP80;Mediator of RNA polymerase II transcription subunit 17;Activator-recruited cofactor 77 kDa component;ARC77;Cofactor required for Sp1 transcriptional activation subunit 6;CRSP complex subunit
背景:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq, Jul 2008],


微信客服