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货号: PD6568
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类：
靶点: CD137L
应用： WB,IF,ELISA
反应性 ： Human,Mouse
宿主物种 ： Rabbit
MW(Observed)： 23kD
同种型-Isotype ： IgG
隐藏域元素占位
详细信息
推荐稀释比 ： WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： CD137L Polyclonal Antibody detects endogenous levels of CD137L protein.
基因名称 ： TNFSF9
蛋白名称 ： Tumor necrosis factor ligand superfamily member 9
别名 ： TNFSF9;Tumor necrosis factor ligand superfamily member 9;4-1BB ligand;4-1BBL
背景：
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided b
细胞定位 ： Membrane; Single-pass type II membrane protein.
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