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货号: PD6736
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: BRG1
应用: WB,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 200kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-2000;IF/ICC1:100-500;ELISA 1:5000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : Brg-1 Polyclonal Antibody detects endogenous levels of Brg-1 protein.
基因名称 : SMARCA4
蛋白名称 : Transcription activator BRG1
别名 : SMARCA4;BAF190A;BRG1;SNF2B;SNF2L4;Transcription activator BRG1;ATP-dependent helicase SMARCA4;BRG1-associated factor 190A;BAF190A;Mitotic growth and transcription activator;Protein BRG-1;Protein brahma homolog 1;SNF2-beta;SWI/S
背景:
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012],


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