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BIG2 Polyclonal Antibody

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说明书下载
货号: PD6765
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: BIG2
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 210kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : BIG2 Polyclonal Antibody detects endogenous levels of BIG2 protein.
基因名称 : ARFGEF2
蛋白名称 : Brefeldin A-inhibited guanine nucleotide-exchange protein 2
别名 : ARFGEF2;ARFGEP2;BIG2;Brefeldin A-inhibited guanine nucleotide-exchange protein 2;Brefeldin A-inhibited GEP 2;ADP-ribosylation factor guanine nucleotide-exchange factor 2

数据库链接:

Organism

基因 ID

SwissProt

背景:

ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm. Membrane. Golgi apparatus. Cytoplasm, perinuclear region. Golgi apparatus, trans-Golgi network . Endosome . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, dendrite . Cytoplasmic vesicle . Cell junction, synapse . Cytoplasm, cytoskeleton . Translocates from cytoplasm to membranes upon cAMP treatment. Localized in recycling endosomes.

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