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详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : BAM32 Polyclonal Antibody detects endogenous levels of BAM32 protein.
基因名称 : DAPP1
蛋白名称 : Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
别名 : DAPP1;BAM32;HSPC066;Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide;hDAPP1;B lymphocyte adapter protein Bam32;B-cell adapter molecule of 32 kDa
背景:
function:May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K.,induction:Upon B-cell activation.,PTM:Phosphorylated on tyrosine residues.,similarity:Contains 1 PH domain.,similarity:Contains 1 SH2 domain.,subcellular location:Membrane-associated after cell stimulation leading to its translocation.,subunit:Interacts with PtdIns(3,4,5)P3 and PLCG2. In vitro, interacts with PtdIns(3,4)P2.,tissue specificity:Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.,


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