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货号: PD6828
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: ATP-citrate synthase
应用: WB,IF,ELISA
反应性 : Human,Mouse,Rat,Monkey
宿主物种 : Rabbit
MW(Observed): 120kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : ATP-citrate synthase Polyclonal Antibody detects endogenous levels of ATP-citrate synthase protein.
基因名称 : ACLY
蛋白名称 : ATP-citrate synthase
别名 : ACLY;ATP-citrate synthase;ATP-citrate;pro-S-;-lyase;ACL;Citrate cleavage enzyme
背景:
ATP citrate lyase(ACLY) Homo sapiens ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2014],


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