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APPL1 Polyclonal Antibody

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说明书下载
货号: PD6953
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: APPL1
应用: WB,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 80kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : APPL1 Polyclonal Antibody detects endogenous levels of APPL1 protein.
基因名称 : APPL1
蛋白名称 : DCC-interacting protein 13-alpha
别名 : APPL1;APPL;DIP13A;KIAA1428;DCC-interacting protein 13-alpha;Dip13-alpha;Adapter protein containing PH domain;PTB domain and leucine zipper motif 1

数据库链接:

Organism

基因 ID

SwissProt

背景:

adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1(APPL1) Homo sapiens The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq, Jul 2008],

细胞定位 : Early endosome membrane ; Peripheral membrane protein . Nucleus . Cytoplasm . Endosome . Cell projection, ruffle . Cytoplasmic vesicle, phagosome . Early endosomal membrane-bound and nuclear. Translocated into the nucleus upon release from endosomal membranes following internalization of EGF. .

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