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货号: PD6966
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: APOBEC3A
应用: WB,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 26kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : APOBEC3A Polyclonal Antibody detects endogenous levels of APOBEC3A protein.
基因名称 : APOBEC3A
蛋白名称 : Probable DNA dC->dU-editing enzyme APOBEC-3A
别名 : APOBEC3A;Probable DNA dC->dU-editing enzyme APOBEC-3A;Phorbolin-1
背景:
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided b


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