产品服务
信号通路
说明书下载
货号: PD6977
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: APBA2BP
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 44kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:40000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : APBA2BP Polyclonal Antibody detects endogenous levels of APBA2BP protein.
基因名称 : NECAB3
蛋白名称 : N-terminal EF-hand calcium-binding protein 3
别名 : NECAB3;APBA2BP;NIP1;SYTIP2;XB51;N-terminal EF-hand calcium-binding protein 3;Amyloid beta A4 protein-binding family A member 2-binding protein;Nek2-interacting protein 1;Neuronal calcium-binding protein 3;X11L-binding protein 51
背景:
The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],


微信客服