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ACCα Polyclonal Antibody

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说明书下载
货号: PD7131
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: ACCα
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 265kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : ACCα Polyclonal Antibody detects endogenous levels of ACCα protein.
基因名称 : ACACA
蛋白名称 : Acetyl-CoA carboxylase 1;ACC1;Acetyl-Coenzyme A carboxylase alpha;ACC-alpha;
别名 : ACACA;ACAC;ACC1;ACCA;Acetyl-CoA carboxylase 1;ACC-alpha;

数据库链接:

Organism

基因 ID

SwissProt

背景:

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

细胞定位 : Cytoplasm, cytosol .

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