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推荐稀释比 ： IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： A Cyclase V/VI Polyclonal Antibody detects endogenous levels of A Cyclase V/VI protein.
基因名称 ： ADCY5/ADCY6
蛋白名称 ： Adenylate cyclase type 5/6
别名 ： ADCY6;KIAA0422;Adenylate cyclase type 6;ATP pyrophosphate-lyase 6;Adenylate cyclase type VI;Adenylyl cyclase 6;Ca;2+;-inhibitable adenylyl cyclase;ADCY5;Adenylate cyclase type 5;ATP pyrophosphate-lyase 5;Adenylate cyclase type V;
数据库链接：
背景：
This gene encodes a member of the adenylyl cyclase family of proteins, which are required for the synthesis of cyclic AMP. All members of this family have an intracellular N-terminus, a tandem repeat of six transmembrane domains separated by a cytoplasmic loop, and a C-terminal cytoplasmic domain. The two cytoplasmic regions bind ATP and form the catalytic core of the protein. Adenylyl cyclases are important effectors of transmembrane signaling pathways and are regulated by the activity of G protein coupled receptor signaling. This protein belongs to a small subclass of adenylyl cyclase proteins that are functionally related and are inhibited by protein kinase A, calcium ions and nitric oxide. A mutation in this gene is associated with arthrogryposis multiplex congenita. [provided by RefSeq, May 2015],
细胞定位 ： Cell membrane ; Multi-pass membrane protein . Cell projection, cilium . Cell projection, stereocilium .
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