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详细信息
修饰-Modification : Phospho
推荐稀释比 : WB 1:1000-2000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : This antibody detects endogenous levels of Human Mouse NF-κB2 p100 (phospho-Ser866 or 870)
基因名称 : NFKB2 LYT10
蛋白名称 : NF-κB2 p100 (Ser866/870)
别名 : NFKB2;LYT10;Nuclear factor NF-kappa-B p100 subunit;DNA-binding factor KBF2;H2TF1;Lymphocyte translocation chromosome 10 protein;Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2;Oncogene Lyt-10;Lyt10;[Cleaved into: Nuclear factor NF-kappa-B p52 subunit]
背景:
nuclear factor kappa B subunit 2(NFKB2) Homo sapiens This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013],


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