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详细信息
修饰-Modification : Phospho
推荐稀释比 : IHC 1:100-1:300;ELISA 1:10000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : Phospho-Caspase-2 (S157) Polyclonal Antibody detects endogenous levels of Caspase-2 protein only when phosphorylated at S157.
基因名称 : CASP2
蛋白名称 : Caspase2
别名 : CASP2;ICH1;NEDD2;Caspase-2;CASP-2;Neural precursor cell expressed developmentally down-regulated protein 2;NEDD-2;Protease ICH-1
背景:
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011],


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