产品服务
信号通路
说明书下载
货号: PF1309
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: PLCG2
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(Observed): 148kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
修饰-Modification : Phospho
推荐稀释比 : WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : Phospho-PLC γ2 (Y753) Polyclonal Antibody detects endogenous levels of PLC γ2 protein only when phosphorylated at Y753.
基因名称 : PLCG2
蛋白名称 : 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2
别名 : PLCG2;1-phosphatidylinositol 4;5-bisphosphate phosphodiesterase gamma-2;Phosphoinositide phospholipase C-gamma-2;Phospholipase C-IV;PLC-IV;Phospholipase C-gamma-2;PLC-gamma-2
背景:
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014],


微信客服