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PDLIM5 (phospho Tyr251) Polyclonal Antibody

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说明书下载
货号: PF1693
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: PDLIM5
应用: WB,ELISA,IHC
反应性 : Human,Rat,Mouse,
宿主物种 : Rabbit
MW(Observed): 64kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

修饰-Modification : Phospho
推荐稀释比 : WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : Phospho-PDLIM5 (Y251) Polyclonal Antibody detects endogenous levels of PDLIM5 protein only when phosphorylated at Y251.
基因名称 : PDLIM5
蛋白名称 : PDZ and LIM domain protein 5
别名 : PDLIM5;ENH;L9;PDZ and LIM domain protein 5;Enigma homolog;Enigma-like PDZ and LIM domains protein

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a member of a family of proteins that possess a 100-amino acid PDZ domain at the N terminus and one to three LIM domains at the C-terminus. This family member functions as a scaffold protein that tethers protein kinases to the Z-disk in striated muscles. It is thought to function in cardiomyocyte expansion and in restraining postsynaptic growth of excitatory synapses. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012],

细胞定位 : Cell junction, synapse, postsynaptic density . Cell junction, synapse, presynapse . Cell junction, synapse, postsynapse . Cytoplasm, cytosol . Detected both at presynaptic and postsynaptic sites, exclusively at excitatory synapses, but not inhibitory synapses, in hippocampal neurons. .

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