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N2DL2 Polyclonal Antibody

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说明书下载
货号: PG6666
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: N2DL2
应用: WB,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(Observed): 27kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:500-2000;ELISA 1:5000-20000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : N2DL2 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : ULBP2 N2DL2 RAET1H UNQ463/PRO791
蛋白名称 : NKG2D ligand 2 (N2DL-2) (NKG2DL2) (ALCAN-alpha) (Retinoic acid early transcript 1H) (UL16-binding protein 2)

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a major histocompatibility complex (MHC) class I-related molecule that binds to the NKG2D receptor on natural killer (NK) cells to trigger release of multiple cytokines and chemokines that in turn contribute to the recruitment and activation of NK cells. The encoded protein undergoes further processing to generate the mature protein that is either anchored to membrane via a glycosylphosphatidylinositol moiety, or secreted. Many malignant cells secrete the encoded protein to evade immunosurveillance by NK cells. This gene is located in a cluster of multiple MHC class I-related genes on chromosome 6. [provided by RefSeq, Jul 2015],

细胞定位 : Cell membrane ; Lipid-anchor, GPI-anchor . Endoplasmic reticulum . Secreted . In CMV-infected fibroblasts, detected in the endoplasmic reticulum/cis-Golgi. .

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