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详细信息
修饰-Modification : Acetyl
推荐稀释比 : WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : Acetyl-Cytokeratin-pan (K194) Polyclonal Antibody detects endogenous levels of Cytokeratin protein only when acetylated at K194.
基因名称 : KRT2/KRT76/KRT3/KRT5/KRT6A/KRT6B/KRT6C/KRT71/KRT72/KRT73/KRT74/KRT75/KRT79/KRT8/KRT84
蛋白名称 : Keratin type II cytoskeletal 2 epidermal/Keratin type II cytoskeletal 2 oral/Keratin type II cytoskeletal 3/Keratin type II cytoskeletal 5/Keratin type II cytoskeletal 6A
别名 : KRT2;KRT2A;KRT2E;Keratin, type II cytoskeletal 2 epidermal;Cytokeratin-2e;CK-2e;Epithelial keratin-2e;Keratin-2 epidermis;Keratin-2e;K2e;Type-II keratin Kb2;KRT76;KRT2B;KRT2P;Keratin, type II cytoskeletal 2 oral;Cytokeratin-2PCK-2P;K2P;Keratin-76;K76;Type-II keratin Kb9;KRT3;Keratin, type II cytoskeletal 3;65 kDa cytokeratin;Cytokeratin-3;CK-3;Keratin-3;K3;Type-II keratin Kb3;KRT5;Keratin, type II cytoskeletal 5;58 kDa cytokeratin;Cytokeratin-5;CK-5;Keratin-5
数据库链接:
背景:
keratin 2(KRT2) Homo sapiens The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008],


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