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Cytokeratin 8&18 (ABT053/CK18) mouse mAb

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说明书下载
货号: PH0105
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Cytokeratin 8/18
应用: IHC,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Mouse
MW(Observed): 48kD,54kD
同种型-Isotype : IgG2b,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-400;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT053/CK18

抗原&靶点信息

特异性 : This product can specifically recognize human CK8 and CK18 protein. It is a cocktail of anti-CK8 and anti-CK18 monoclonal antibodies.
基因名称 : KRT8/KRT18

数据库链接:

Organism

基因 ID

SwissProt

背景:

keratin 8(KRT8) Homo sapiens This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012],

细胞定位 : Cytoplasmic, Membranous

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