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货号: PL0207
货期: 现货
价格: 100μL/1800
所属分类:
靶点: IL-17Rα
应用: WB,IF,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(CalcμLated) : 96kD
MW(Observed): 120-170kD
同种型-Isotype : IgG,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal
抗原&靶点信息
特异性 : Endogenous
基因名称 : IL17RA
蛋白名称 : Interleukin-17 receptor A
别名 : IL17RA;IL17R;Interleukin-17 receptor A;IL-17 receptor A;IL-17RA;CDw217;CD antigen CD217
背景:
Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014],


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