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Caspase-11 (PT1565R) PT™ Rabbit mAb

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说明书下载
货号: PL0211
货期: 现货
价格: 100μL/1800
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靶点: Caspase-11
应用: WB,IHC,IF,ELISA
反应性 : Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 43kD
MW(Observed): 42kD
同种型-Isotype : IgG,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal

抗原&靶点信息

特异性 : Endogenous
基因名称 : CASP4 ICH2
蛋白名称 : CASP4(Caspase4)
别名 : CASP4;ICH2;Caspase-4;CASP-4;ICE;rel;-II;Protease ICH-2;Protease TX

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the cysteine proteases that plays important roles in apoptosis, cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is "caspase 4, apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9. [provided by RefSeq, Apr 2015]

细胞定位 : Cytoplasm. Endoplasmic.reticulum.Inflammasome.Membrane.Mitochondrion.Secreted

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