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BST-2 (PT1560R) PT™ Rabbit mAb

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说明书下载
货号: PL0216
货期: 现货
价格: 100μL/1800
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靶点: BST-2
应用: WB,IHC,IF,IP,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(CalcμLated) : 20kD
MW(Observed): 28-40kD(monomer),50-70kD(dimer)
同种型-Isotype : IgG,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:500-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal

抗原&靶点信息

特异性 : Endogenous
基因名称 : BST2
蛋白名称 : Bone marrow stromal antigen 2
别名 : BST2;Bone marrow stromal antigen 2;BST-2;HM1.24 antigen;Tetherin;CD317

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008],

细胞定位 : Golgi apparatus, trans-Golgi network. Cell membrane ; Single-pass type II membrane protein. Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft. Cytoplasm. Apical cell membrane . Shuttles between the cell membrane, where it is present predominantly in membrane/lipid rafts, and the trans-Golgi network. Forms a complex with MMP14 and localizes to the cytoplasm.; Golgi apparatus, trans-Golgi network . Late endosome . (Microbial infection) HIV-1 VPU and HIV-2 ENV can target it to the trans-Golgi network thus sequestering it away from virus assembly sites on the cell membrane. Targeted to late endosomes upon KSHV infection and subsequent ubiquitination. .

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