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Progesterone Receptor(PR) (PT1536R) PT™ Rabbit mAb

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说明书下载
货号: PL0239
货期: 现货
价格: 100μL/1800
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靶点: PR
应用: WB,IHC,IF,IP,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(CalcμLated) : 99kD
MW(Observed): 118kD
同种型-Isotype : IgG,Kappa

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:200-1:1000;WB 1:10000-1:50000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : Monoclonal

抗原&靶点信息

特异性 : Endogenous
基因名称 : PGR;NR3C3
蛋白名称 : Progesterone Receptor(PR)
别名 : PGR;NR3C3;Progesterone receptor;PR;Nuclear receptor subfamily 3 group C member 3

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq, Sep 2015],

细胞定位 : Nucleus. Cytoplasm. Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases.; [Isoform A]: Nucleus. Cytoplasm. Mainly nuclear.; [Isoform 4]: Mitochondrion outer membrane .

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