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Dnmt3a Rabbit mAb

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说明书下载
货号: PL0776
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: DNM3A
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 102kD
MW(Observed): 130kD
同种型-Isotype : IgG, Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:100-1:500;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : PT1011R

抗原&靶点信息

特异性 : Endogenous
基因名称 : DNMT3A
蛋白名称 : DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016],

细胞定位 : Nucleus . Chromosome . Cytoplasm . Accumulates in the major satellite repeats at pericentric heterochromatin. .

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