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货号: PL0834
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
靶点: NDUFS1
应用: WB,IHC,IF,IP,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 80kD
MW(Observed): 77kD
同种型-Isotype : IgG, Kappa
偶联-Conjugate : Unmodified
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : PT0942R
抗原&靶点信息
特异性 : Endogenous
基因名称 : NDUFS1
蛋白名称 : NADH-ubiquinone oxidoreductase 75 kDa subunit mitochondrial
别名 : NDUFS1;NADH-ubiquinone oxidoreductase 75 kDa subunit;mitochondrial;Complex I-75kD;CI-75kD
背景:
The protein encoded by this gene belongs to the complex I 75 kDa subunit family. Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. This protein is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized. Mutations in this gene are associated with complex I deficiency. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011],


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