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MCP-1 Rabbit mAb

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说明书下载
货号: PL0904
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: MCP1
应用: WB,IHC,IF,IP,ELISA
反应性 : Human
宿主物种 : Rabbit
MW(CalcμLated) : 11kD
MW(Observed): 11kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:2000-1:10000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆号 : PT0877R

抗原&靶点信息

特异性 : Endogenous
基因名称 : MCP1, SCYA2,CCL2
蛋白名称 : MCP1;Monocyte chemoattractant protein 1;Monocyte chemotactic protein 1;Monocyte secretory protein JE

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection. [provided by RefSeq, Aug 2020]

细胞定位 : Secreted

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