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详细信息
推荐稀释比 : IHC 1:1000-1:5000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0701R
抗原&靶点信息
特异性 : Endogenous
基因名称 : GPER1
蛋白名称 : G-protein coupled estrogen receptor 1
别名 : G-protein coupled estrogen receptor 1;Chemoattractant receptor-like 2;Flow-induced endothelial G-protein coupled receptor 1;FEG-1;G-protein coupled receptor 30;GPCR-BR;IL8-related receptor DRY12;Lymphocyte-derived G-protein coupled receptor;LYGPR;Membrane estrogen receptor;mER;
背景:
This gene is a member of the G-protein coupled receptor 1 family and encodes a multi-pass membrane protein that localizes to the endoplasmic reticulum. The protein binds estrogen, resulting in intracellular calcium mobilization and synthesis of phosphatidylinositol 3,4,5-trisphosphate in the nucleus. This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen. Alternate transcriptional splice variants which encode the same protein have been characterized. [provided by RefSeq, Jul 2008],


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