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详细信息
推荐稀释比 : IHC 1:200-1:1000;WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0691R
抗原&靶点信息
特异性 : Endogenous
基因名称 : PPP1CA;PPP1CB
蛋白名称 : Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;Serine/threonine-protein phosphatase PP1-beta catalytic subunit;
别名 : PPP1CA;PPP1A;Serine/threonine-protein phosphatase PP1-alpha catalytic subunit;PP-1A;PPP1CB;Serine/threonine-protein phosphatase PP1-beta catalytic subunit;PP-1B;PPP1CD;
数据库链接:
Organism
基因 ID
SwissProt
背景:
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],


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