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Fascin Rabbit mAb

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说明书下载
货号: PL1220
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: Fascin
应用: WB,IHC,IF,IP,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 54kD
MW(Observed): 54kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:1000-1:5000;WB 1:10000-1:20000;IF 1:200-1:1000;ELISA 1:5000-1:20000;IP 1:50-1:200;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0620R

抗原&靶点信息

特异性 : Endogenous
基因名称 : FSCN1 FAN1 HSN SNL
蛋白名称 : Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],

细胞定位 : Cytoplasmic

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