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MEK4 Rabbit mAb

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说明书下载
货号: PL1148
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: MEK-4
应用: WB,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 44kD
MW(Observed): 44kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : WB 1:2000-1:10000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0589R

抗原&靶点信息

特异性 : Endogenous
基因名称 : MAP2K4
蛋白名称 : Dual specificity mitogen-activated protein kinase kinase 4
别名 : Dual specificity mitogen-activated protein kinase kinase 4;MAP kinase kinase 4;MAPKK 4;JNK-activating kinase 1;MAPK/ERK kinase 4;MEK 4;SAPK/ERK kinase 1;SEK1;Stress-activated protein kinase kinase 1;SAPK kinase 1;SAPKK-1;SAPKK1;c-Jun N-terminal kinase kinase 1;JNKK;

数据库链接:

Organism

基因 ID

SwissProt

背景:

This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

细胞定位 : Cytoplasm, Nucleus

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