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HLA-DR Rabbit mAb

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说明书下载
货号: PL1319
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: HLA-DRA
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Rabbit
MW(CalcμLated) : 29kD
MW(Observed): 37kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:1000-1:4000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0377R

抗原&靶点信息

特异性 : Endogenous
基因名称 : HLA-DRA HLA-DRA1
蛋白名称 : HLA class II histocompatibility antigen, DR alpha chain (MHC class II antigen DRA)

数据库链接:

Organism

基因 ID

SwissProt

背景:

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Jul 2008],

细胞定位 : Membrane

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