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货号: PL1448
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: MMP-13
应用: WB,IHC,IF,ELISA
反应性 : Human,Mouse,
宿主物种 : Rabbit
MW(CalcμLated) : 60kD
MW(Observed): 60kD
同种型-Isotype : IgG,Kappa
偶联-Conjugate : Unmodified
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:100-500;WB 1:500-2000;IF 1:200-1000;ELISA 1:5000-20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0161R
抗原&靶点信息
特异性 : Endogenous
基因名称 : MMP13
蛋白名称 : Collagenase 3
别名 : MMP13;Collagenase 3;Matrix metalloproteinase-13;MMP-13
背景:
This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016],


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