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详细信息
推荐稀释比 : IHC 1:20-100;WB 1:1000-5000;IF 1:200-1000;ELISA 1:5000-20000;
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : Protein A
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : PT0142R
抗原&靶点信息
特异性 : Endogenous
基因名称 : PROM1
蛋白名称 : Prominin-1
别名 : PROM1;Prominin-1;Antigen AC133;Prominin-like protein 1;CD133
背景:
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],


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