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货号: PH0206
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: S100B
应用: IHC,IF,ELISA
反应性 : Human,Mouse,Rat,
宿主物种 : Mouse
MW(CalcμLated) : 11kD
同种型-Isotype : IgG1,Kappa
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:200-400;IF 1:50-200;ELISA 1:500-5000
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
克隆性 : Monoclonal
克隆号 : ABT-S100B
抗原&靶点信息
特异性 : This antibody detects endogenous levels of S100 protein.
基因名称 : S100B
蛋白名称 : S100
背景:
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy


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