产品服务
信号通路
详细信息
推荐稀释比 : IHC 1:50-300;IF 1:50-200
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : CHD8 Polyclonal Antibody detects endogenous levels of protein.
基因名称 : CHD8 HELSNF1 KIAA1564
蛋白名称 : Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
背景:
This gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta-catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010],


微信客服