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FILA Polyclonal Antibody

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说明书下载
货号: PG5878
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: FILA
应用: IHC,IF
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(Observed): 446kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:50-300;IF 1:50-200
组成 : PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : FILA Polyclonal Antibody detects endogenous levels of protein.
基因名称 : FLG
蛋白名称 : Filaggrin

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009],

细胞定位 : Cytoplasmic granule . In the stratum granulosum of the epidermis, localized within keratohyalin granules (PubMed:1429717). In granular keratinocytes and in lower corneocytes, colocalizes with calpain-1/CAPN1 (PubMed:21531719). .

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