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货号: PD2928
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: β-1/4-Gal-T2
应用: IHC,IF,ELISA
反应性 : Human,Mouse
宿主物种 : Rabbit
MW(CalcμLated) : 42kD
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : IHC 1:100-1:300;ELISA 1:20000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal
抗原&靶点信息
特异性 : β-1,4-Gal-T2 Polyclonal Antibody detects endogenous levels of β-1,4-Gal-T2 protein.
基因名称 : B4GALT2
蛋白名称 : Beta-1,4-galactosyltransferase 2
别名 : B4GALT2;Beta-1;4-galactosyltransferase 2;Beta-1,4-GalTase 2;Beta4Gal-T2;b4Gal-T2;UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2;UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2
背景:
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity i


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