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DOCK 2 Polyclonal Antibody

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说明书下载
货号: PD5992
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: DOCK 2
应用: IHC,IF,ELISA
反应性 : Human,Mouse,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 212kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : DOCK 2 Polyclonal Antibody detects endogenous levels of DOCK 2 protein.
基因名称 : DOCK2
蛋白名称 : Dedicator of cytokinesis protein 2
别名 : DOCK2;KIAA0209;Dedicator of cytokinesis protein 2

数据库链接:

Organism

基因 ID

SwissProt

背景:

The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. [provided by RefSeq, Oct 2016],

细胞定位 : Endomembrane system ; Peripheral membrane protein . Cytoplasm, cytoskeleton . Colocalizes with F-actin.

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