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货号: PF0810
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类：
靶点: Stathmin
应用： IHC,IF,ELISA
反应性 ： Human,Mouse,Rat
宿主物种 ： Rabbit
MW(CalcμLated) ： 21kD
同种型-Isotype ： IgG
隐藏域元素占位
详细信息
修饰-Modification ： Phospho
推荐稀释比 ： IHC 1:100-1:300;ELISA 1:5000;IF 1:50-200
组成 ： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 ： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 ： -15°C to -25°C/1 year(Do not lower than -25°C
浓度 ： 1 mg/ml
克隆性 ： Polyclonal
抗原&靶点信息
特异性 ： Phospho-SCG10 (S73) Polyclonal Antibody detects endogenous levels of SCG10 protein only when phosphorylated at S73.
基因名称 ： STMN2
蛋白名称 ： Stathmin-2
别名 ： STMN2;SCG10;SCGN10;Stathmin-2;Superior cervical ganglion-10 protein;Protein SCG10
背景：
This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6. [provided by RefSeq, Nov 2010],
细胞定位 ： Cytoplasm . Cytoplasm, perinuclear region . Cell projection, growth cone. Membrane ; Peripheral membrane protein ; Cytoplasmic side . Cell projection, axon. Golgi apparatus. Endosome . Cell projection, lamellipodium. Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia. .
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