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INPP5J Polyclonal Antibody

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说明书下载
货号: PD5207
货期: 现货
价格: 50μL/960;100μL/1600;200μL/2560
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靶点: INPP5J
应用: IHC,IF,ELISA
反应性 : Human,Rat
宿主物种 : Rabbit
MW(CalcμLated) : 107kD
同种型-Isotype : IgG

隐藏域元素占位

详细信息

推荐稀释比 : IHC 1:100-1:300;ELISA 1:40000;IF 1:50-200
组成 : Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺 : The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存 : -15°C to -25°C/1 year(Do not lower than -25°C
浓度 : 1 mg/ml
克隆性 : Polyclonal

抗原&靶点信息

特异性 : INPP5J Polyclonal Antibody detects endogenous levels of INPP5J protein.
基因名称 : INPP5J
蛋白名称 : Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A
别名 : INPP5J;PIB5PA;PIPP;Phosphatidylinositol 4;5-bisphosphate 5-phosphatase A;Inositol polyphosphate 5-phosphatase J

数据库链接:

Organism

基因 ID

SwissProt

Mouse
背景:

catalytic activity:1D-myo-inositol 1,3,4,5-tetrakisphosphate + H(2)O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.,catalytic activity:D-myo-inositol 1,4,5-trisphosphate + H(2)O = myo-inositol 1,4-bisphosphate + phosphate.,domain:The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein.,function:Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles.,PTM:Phosphorylated at Ser/Thr residues.,similarity:Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family.,subcellular location:Predominantly localized to membrane ruffles.,

细胞定位 : Cytoplasm . Predominantly localized to membrane ruffles. .

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