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货号: STA02567
货期: 次日发货
价格: 50μL/960;100μL/1600;200μL/2560
所属分类:
靶点: PAG
应用: WB IHC IP FC
反应性 : Human Mouse Rat
宿主物种 : Rabbit
MW(Observed): 80kDa
同种型-Isotype : IgG
隐藏域元素占位
详细信息
推荐稀释比 : WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:100
纯化工艺 : Affinity-chromatography
储存 : Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
克隆性 : Monoclonal
抗原&靶点信息
特异性 : PAG Antibody detects endogenous levels of total PAG
别名 : CBP; Csk binding protein; PAG; PAG1;
数据库链接:
背景:
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins.


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